Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ 1-Pyrrolidinecarbodithioic Acid, Ammonium Salt
Cell permeable. Inhibits the induction of NOS activity in rat alveolar macrophages. Prevents apoptosis in human HL-60 cells and thymocytes, but induces apoptosis in human and rat smooth muscle cells.
MP Biomedicals™ Phosphatase Inhibitor Cocktail, 10X
This Phosphatase Inhibitor Cocktail is suitable for protein extraction from animal cells or tissue and can maintain protein phosphorylation.
MilliporeSigma™ Calbiochem™ HDAC Inhibitor XXIII, Tubastatin A
The HDAC Inhibitor XXIII, Tubastatin A controls the biological activity of HDAC. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ HSP90 Inhibitor, CCT018159
The HSP90 Inhibitor, CCT018159, also referenced under CAS 171009-07-7, controls the biological activity of HSP90.
MilliporeSigma™ Calbiochem™ GPR40 Agonist III
A cell-permeable, highly potent, and selective agonist of free fatty acid receptor 1 (FFA1; GPR40; EC50 = 20 nM in FFA1-transfected HEK-293 cells).
MilliporeSigma™ Calbiochem™ U-73122
U-73122, CAS 112648-68-7, inhibits agonist-induced phospholipase C activation (IC50 = 1 to 2.1 μM) in human platelets and neutrophils.
MilliporeSigma™ Calbiochem™ PRMT Inhibitor VII, DB867
A cell-permeable, selective inhibitor of protein arginine methyltransferase 1 (PRMT1; IC50 = 9.5 μM).
MilliporeSigma™ Calbiochem™ Calpastatin Peptide, Negative Control
A scrambled peptide with an identical amino acid composition to that of Calpastatin Peptide. Useful as a negative control for Calpastatin Peptide.
MilliporeSigma™ Calbiochem™ Protease Inhibitor Cocktail Set I, Animal-Free
The Protease Inhibitor Cocktail Set I, Animal-Free controls the activity of Protease. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Foxo1 Inhibitor, AS1842856
Foxo1 Inhibitor, AS1842856, is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 (IC50 = 33 nM). Directly binds to the active Foxo1, but not the Ser256-phosphorylated form.
MilliporeSigma™ Calbiochem™ 2-Chloro-2'-deoxyadenosine
A deoxyadenosine analog that displays strong antileukemic and immunosuppressive activity.
MilliporeSigma™ Calbiochem™ Rottlerin
Rottlerin, CAS 82-08-6, is a cell-permeable, reversible inhibitor of protein kinase C with greater selectivity for PKCδ(IC50= 3-6μM) and PKCθ. Has about 10-fold lower potency against other isozymes.
MilliporeSigma™ Calbiochem™ InSolution™ Nocodazole
Inhibitor of mitosis. Has highly specific antimicrotubular activity for mammalian cells in culture.
MilliporeSigma™ Calbiochem™ Integrin αvβ3 Antagonist, P11
The Integrin αvβ3 Antagonist, P11 controls the biological activity of Integrin αvβ3.
MilliporeSigma™ Calbiochem™ ICMT Inhibitor
The ICMT Inhibitor controls the biological activity of ICMT. This small molecule/inhibitor is primarily used for Cancer applications.