Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ p38 MAP Kinase Inhibitor X, BIRB 796
The p38 MAP Kinase Inhibitor X, BIRB 796, also referenced under CAS 285983-48-4, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Membrane Traffic Inhibitor, A5
The Membrane Traffic Inhibitor, A5 controls the biological activity of adaptor complex AP-1.
MilliporeSigma™ Calbiochem™ Combretastatin A-4
A synthetic Combretum caffrum-derived cell-permeable stilbenoid phenol that competes with colchicine tubulin binding and interferes with tubulin polymerization as well as cellular microtubule assembly
MilliporeSigma™ Calbiochem™ Glutaminase Inhibitor, Compound 968
Glutaminase Inhibitor, Compd 968, is a cell-permeable, reversible inhibitor of mitochondrial glutaminase. Represses growth & invasive activity in glutaminase upregulated fibroblasts and tumor cells.
MilliporeSigma™ Calbiochem™ Hh/Gli Antagonist, GANT58
The Hh/Gli Antagonist, GANT58, also referenced under CAS 64048-12-0, controls the biological activity of Hh/Gli. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ Shikonin
A naphthoquinone found in the Chinese herb Shiunko.
MilliporeSigma™ Calbiochem™ Cathepsin L Inhibitor II
The Cathepsin L Inhibitor II controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ 1-Pyrrolidinecarbodithioic Acid, Ammonium Salt
Cell permeable. Inhibits the induction of NOS activity in rat alveolar macrophages. Prevents apoptosis in human HL-60 cells and thymocytes, but induces apoptosis in human and rat smooth muscle cells.
MilliporeSigma™ Calbiochem™ ACE2 Inhibitor, MLN-4760
A cell-permeable, highly potent inhibitor of angiotensin converting enzyme 2 (ACE2; IC50 = 440 pM).
MilliporeSigma™ Calbiochem™ Windorphen
A cell-permeable, selective inhibitor p300 histone acetytransferase (IC50 = 4.2μM)
MilliporeSigma™ Calbiochem™ Cathepsin D/E Substrate, Fluorogenic
An internally quenched fluorogenic 11-mer peptide that acts as a sensitive and selective substrate for cathepsins D and E, but not cathepsins B, H, or L .
MilliporeSigma™ Calbiochem™ Daidzein
Inactive analog of Genistein.
MilliporeSigma™ Calbiochem™ RPA Inhibitor, TDRL-505
A cell-permeable compound that targets human Replication Protein A (RPA) and inhibits its DNA-binding activity (IC50 12.9 μM).
MilliporeSigma™ Calbiochem™ Cyclopamine, V. californicum
Cyclopamine, V. californicum, CAS 4449-51-8, is a cell-permeable steroidal alkaloid & cholesterol mimic that specifically antagonizes Sonic Hedgehog signaling through direct interaction with Smo.
MilliporeSigma™ Calbiochem™ α,β-methylene ATP
A metabolically stable and selective P2X purinergic receptor agonist (pEC50